GLP-1 Side Effects

January 2026 · 5 min read

TL;DR: Common: nausea, diarrhea, constipation. Usually improve in 4-8 weeks. Gradual dosing minimizes effects.

Understanding GLP-1 side effects prepares you for treatment.

Common Side Effects

Rare but Serious

Seek Medical Attention: Severe abdominal pain, persistent vomiting, signs of allergic reaction.
Medical Disclaimer: Report any concerning symptoms to your doctor.

References

  1. Jastreboff AM, et al. Tirzepatide Once Weekly for the Treatment of Obesity (clinical research-1). N Engl J Med. 2022.
  2. Garvey WT, et al. Tirzepatide Once Weekly for the Treatment of Obesity in People with Type 2 Diabetes (clinical research-2). Lancet. 2023.

Medically Reviewed by Dr. Adaobi Chukwu, MBBS, FMCP

Gastroenterology - Side Effects Specialist

Content reviewed by qualified healthcare professionals for accuracy.